Malcom in the Middle (2000-2006)
Since the show ended:
Erik Per Sullivan (Dewey): Made limited television appearances while finishing high school. Attended the University of Southern California for 2 semesters before dropping out. Last television appearance: 2010
Christopher Masterson (Francis): Made only a few television and movie appearances including a direct-to-DVD movie starring himself and brother Danny (of That 70’s Show fame). Converted to Scientology along with his brother. Last television appearance: 2012
Justin Barfield (Reese): Made a few minor television and movie appearances before moving into the role of a producer, including becoming executive producer of the short live FOX series Sons of Tucson. In 2010 he was hired by Virgin Group as the Chief Creative Officer for their new Virgin Produced film and entertainment company, a position he still holds.
Frankie Muniz (Malcolm): Has made several film and television appearances since the show’s end. He began a short-lived career in American Formula racing in 2007, racing for his last team in 2009. Muniz has continued pursuing his interests including having joined the band Kingsfoil in 2012 but has suffered significant health problems, including 2 “mini-strokes”, most recently in November 2013.
Jane Kaczmarek (Lois): Co-starred in the TNT television seriesRaising the Barfrom 2008-2009. Kaczmarek has guest starred in multiple television shows, including recurring roles onWhitney, The Simpsons,andThe Middle. She received nominations for Best Lead Actress in Play for her portrayal as Margie in the Los Angeles production ofGood People.In 2014 she will co-star in the new Fox comedy seriesUs and Them.
Bryan Cranston (Hal): Since the show’s end Cranston has been cast in many films, including Argo, The Lincoln Lawyer, Drive, John Carter, and Total Recall. Most prominently (and among more than a dozen other television roles) he is now known for his lauded portrayal as Walter White on the AMC series Breaking Bad. His portrayal as the cancer stricken teacher turned meth producer earned him 3 consecutive Primetime Emmy Awards for Lead Actor (becoming the second person to ever to so and first since Bill Cosby from 1966-1968 for his work on I Spy). He also won an Emmy Award as producer of the show for its final season. He is slated to co-star in multiple films including the upcoming 2014 remake of Godzilla,the crime thriller Cold is the Night, and is confirmed to have a role in the upcoming Kung-Fu Panda 3. Like his female counterpart, Cranston has also made a return to the stage starring as President Lyndon Johnson in the American Repertory Theatre’s production ofAll the Way which is featured in their 2013-2014 season.